Sentence examples for abrogation as from inspiring English sources

Anticancer insights derived from cell cycle research have given birth to the idea of cell cycle G2 checkpoint abrogation as a cancer-cell-specific therapy.

In Tg197 mice, it significantly (P < 0.05) moderates histopathologic score of synovitis, cartilage destruction and bone erosion, but fails to show appreciable abrogation of AS.

Tumors activate HIFα either in the face of hypoxia resulting from poor vascularization or due to genetic abrogation such as VHL loss (Gordan and Simon, 2007).

Among those culpable of such behavior, the abrogation of the obligation as well as the right to free speech, an indictment should single out those who are paid to think and to communicate.

We further demonstrated that mTORC1 inactivation and subsequent autophagy induction act as an overall survival signal, as abrogation of autophagy led to an increased suppression of tumor growth by enhancing apoptosis induction.

This may account for tiron's abrogation of bortezomib-induced toxicity as well as the lack of effect on toxicity induced by non-boronated MG132.

John was incensed about what he perceived as an abrogation of his customary right as monarch to influence the election.

As abrogation and inhibition of caspase-1 by either a knockout approach or pralnacasan treatment did not have any effect in our model, the role of caspase-1/the inflammasome appears not to be as crucial as suggested.

Any variation in binding or the total abrogation of binding, as a result of this adjacent Ser/Thr phosphorylation, may indicate that a stimulation-specific interaction exists between c-Cbl and its particular substrate.

Expression of dCR4h resulted in mild abrogation of COC, as predicted by high frequency of spindle misoreintation upon expression of dCR4h.

Accumulation of these cells is dependent on the SAC as abrogation of SAC by mad2 deletion enabled cells to progress to anaphase with spindles of aberrant morphology.