The phrase "abrogation ability" is correct and usable in written English.
It can be used in contexts discussing the capacity or power to annul or repeal laws, agreements, or regulations.
Example: "The new legislation grants the committee the abrogation ability to nullify outdated policies."
Alternatives: "power to repeal" or "capacity for annulment."
Indeed, elimination of this motif from bacterial HspH leads to the complete abrogation of the ability of the protein to oligomerise and chaperone amorphously aggregating citrate synthase [56].
mTerc−/− mice are lacking the RNA component of telomerase, which leads to an abrogation of the ability to elongate telomeres during cell division.
One interpretation of our data is that abrogation of the ability of Akt to phosphorylate the Tsc1/2 complex has no functional consequences whatsoever for the animal.
As seen in Figure 11, depletion of α-SMA resulted in both decreased basal cell motility (86% ±6%p<0.01 compared to no treatment) and in an abrogation of the ability of the cell to respond to the EGF motive stimulus (to 94% ±4%p<0.001).
Longer carbamylation times (6, 9 or 12 h) resulted in complete abrogation of the ability of IgG1 to bind C1q.
Likewise, in S. pneumoniae, abrogation of the ability to uptake glutathione (Spn does not biosynthesize GSH) gives rise to a severe growth defect under copper stress.
In addition, Cdkn2a mutation led to widespread and sustained epithelial hyperplasia (Fig 5B) and a complete abrogation of the ability of V600EBraf to induce crypt senescence as assessed by the lack of SA-β-galactosidase staining (Fig 5C).
There is also a role for VE-cadherin and Ephrin A2 since downregulation of these genes in melanoma cells resulted in an abrogation of their ability to form vasculogenic-like structures [ 101].
Negative regulation of the NF-κB pathway through inhibition of IκB kinase (IKK) and abrogation of the DNA binding ability of NF-κB, has emerged as a major pathway of PPARγ-independent 15-PGJ2 activity (Petrova et al, 1999; Castrillo et al, 2000; Rossi et al, 2000; Straus et al, 2000; Boyault et al, 2001; Janabi, 2002;).
The ability to accomplish selective abrogation of oncogenes by the use of intracellular sFvs opens a wide variety of possibilities in breast cancer investigation and therapy.
