The phrase "abrogated upon" is not commonly used in written English and may sound awkward or unclear.
It can be used in legal or formal contexts to indicate that something has been formally repealed or annulled under certain conditions.
Example: "The treaty was abrogated upon the discovery of violations by one of the parties involved."
Alternatives: "nullified upon" or "repealed upon".
The difference in anticandidal effector functions observed between TLR2−/− and TLR2+/+ macrophages is abrogated upon opsonization of the fungal target and interestingly is not observed when using other microbial targets, such as Streptococcus pneumoniae and Helicobacter pylori.
Immunization with LV305 protected mice against tumor growth in an NY-ESO-1-expressing CT26 lung metastasis model, with the protective effect abrogated upon depletion of CD8 T cells.
Correlating with these findings, while we found that the crizotinib ALK binding in RU cells was largely abrogated upon the enforced expression of β-catenin-wt, transfection of ΔN47 into RU cells did not substantially affect the crizotinib ALK binding (Fig. 5C).
This cell death was abrogated upon knock-down of Serk3-like sequences [7].
The transactivation was abrogated upon treatment with the monoclonal antibody HD-1 (Fig. 10b).
It should be mentioned that the pH stability phenotype might be abrogated upon passaging in tissue culture [28].
Only MPA promoted the adhesion of neutrophils onto hECM under basal conditions, and this effect was abrogated in upon blocking β2-integrin/CD18.
These data reveal that lack of caspase-8 or FADD, two essential components of the death receptor pathway, expression of cFLIP-L or resistance to death receptor ligands do not abrogate apoptosis upon Ukrain-treatment.
CST3-overexpressing cells showed a strong reduction in CTSB activity, but this suppression was abrogated by approximately 50% upon CST1 expression.
Interestingly, addition of the cytotoxic anti-Fas antibody to HSV-2-infected keratinocyte and epithelial cultures significantly abrogated CXCL1/2 expression, whereas, upon these conditions, TNF- α and IL-1 β expression was abrogated only in keratinocytes (P≤0.05, Figures 7a d).
Stable expression of the HPV16 E6 viral oncoprotein, which destabilizes and eliminates p53 function, abrogated induction of luciferase activity upon transfection of p53 (Figure 1a, middle panel).
