Sentence examples for abrogated to show from inspiring English sources

We have to further confirm the effect of DNA damage response when TFII-I is abrogated to show its involvement in this mechanism.

To check the requirement for H3.3, they injected into the oocyte polyclonal antibodies against HIRA, the chaperone responsible for the incorporation of histone H3.3 into chromatin, and were able to show that this abrogates transcriptional reprogramming.

These data challenge suggested models to the contrary, which have not yet been definitively tested with antagonistic anti-TRAIL antibodies to show that TRAIL inhibition abrogates apoptosis in uninfected cells.

GTCpFE, at concentrations where MS formation is completely abrogated, showed little to no effect on viability of adherent parental cells.

BRCA1 expression was effectively abrogated, as shown in Western blot analyses (Fig 1A).

Accordingly, CD3 surface down-modulation was significantly inhibited following PD-1 silencing in stimulated GFP+ CD4+ T cells, although not completely abrogated (results not shown).

We observed that the K191S mutation that abrogates ATP binding showed similar mRNA binding compared to the wild-type protein.

The use of small-molecule inhibitors to abrogate ILK activity has been shown to reverse ILK oncogenic effects in animal model studies and clinical trials (Muranyi et al, 2009; Cox et al, 2010).

Both PrioV3 antibody and ICSM35 completely abrogated PrPSc replication as shown by Western blot.

As with previous datasets shuffling the transcript dataset abrogated this signal (not shown).

The mutation of lysine 41 to glutamic acid in SCR 1 of CR2 (K41E CR2) has previously been shown to abrogate binding to C3d.