Sentence examples for abrogated at from inspiring English sources

It is the guarantee from one generation to the next that our rights cannot simply be abrogated at the whims of others or the fashion of the times.

This suppressive activity was abrogated at 30 or 100 days after LTx.

Interestingly, the effect of MSC concentrate was abrogated at higher cell masses indicating a therapeutic window of effectiveness.

Progression to meiosis I in zmm mutants in the SK1 background is more severely abrogated at 33°C than at 23°C.

Suppression was observed with concentrations as low as 0.06 µg/ml, Th17 development was almost entirely abrogated at 1 µg/ml and the EC50 of anti-CD28 mAb was 0.1 µg/ml (Fig. 3A, left).

In situ hybridization for Fgf, Notch, RA, Bmp and Hedgehog target genes such as pea3, neuroD, krox20, msx1 and ptc1 was done in inhibitor-treated embryos to confirm that each signaling pathway was abrogated at our working concentrations (Figure S2).

Knocking down ROCK1 expression using a ROCK1-specific siRNA also significantly abrogated AT-101-mediated apoptosis.

Knocking down ROCK1 expression significantly abrogated AT-101-mediated apoptosis and diminished AT-101-induced PARP cleavage, caspase activation, and cytochrome c release.

In the present study, treating U937 cells with both z-VAD-fmk, a caspase inhibitor, and AT-101 abrogated the AT-101-induced caspase-3 activation and apoptosis and failed to prevent ROCK1 cleavage/activation.

BAG-1 regulates the chaperone function of HSC70 and HSP70 (Hohfeld, 1998) and mutation of specific amino-acid residues important for binding to chaperone proteins abrogates at least some BAG-1 functions (Briknarova et al, 2001).

Thus, the VPS33B c.1225+5G>C) mutation seems to affect the ability of the complexes to colocalize properly on tubular vesicular recycling membranes, which is likely to abrogate at least partially its cellular functioning.