The phrase "abrogate the function of" is correct and usable in written English.
It can be used in contexts where one is discussing the cancellation or annulment of a specific role or responsibility.
Example: "The new policy will abrogate the function of the previous committee, rendering it obsolete."
Alternatives: "nullify the role of" or "invalidate the function of".
Moreover, overexpression of antiapoptotic factors, such as Bcl-2 and Bfl-1, has been demonstrated to abrogate the function of proapoptotic proteins, and elicit a protective effect on host cells [27].
Although macrophages were depleted by clodronate administration, clodronate did not abrogate the function of antigen-presenting cells.
As this domain is located in the TACC domain, the L461A mutation might also abrogate the function of Alp7.
The transcriptional repression ability of ATF3 may then effectively abrogate the function of one or more of these pathways, and thereby initiate the process of tumorigenesis.
Results showed that PfI2(19–144) as well as PfI2W16A were able to completely abrogate the function of PfI2WT as no GVBD was observed.
The ability of this viral oncogene to extend the cellular lifespan has been attributed to its competence to abrogate the function of the cell cycle regulators p53 and pRb.
In RA, the reduction of Sema3A may abrogate the functions of regulatory T cells, thus allowing the infiltration and focal aggregation of autoreactive lymphocytes in the sublining layer.
To address germline-specific functions of essential genes, genetic approaches have been developed to abrogate the functions of specific genes only in germline cells.
Thus, no indication was obtained to suggest that EGFP tagging abrogated the function of the cofilin variants used here, neither in vivo nor in vitro.
In addition to abrogating the function of regulatory cells by blocking their differentiation, accumulation of regulatory cells in the tumour microenvironment can be reduced by targeting chemokine pathways.
Other studies using RNA interference showed that all mutations that disrupted this interaction abrogated the function of the whole complex [ 21].
