The phrase "abrogate iron" is not correct and does not convey a clear meaning in written English.
It is not a commonly used expression and lacks context to determine its intended use.
Example: "The government decided to abrogate iron regulations that were deemed outdated."
Alternatives: "revoke iron" or "cancel iron regulations".
(J ) Expression of HERC22540−2700 abrogates iron-mediated NCOA4 downregulation.
Selective inhibition of BMP6 signaling abrogates iron-induced up-regulation of hepcidin.
It is interesting to note that the administration of dl-cysteine, a reactive oxygen species scavenger, completely abrogated the iron load-induced thrombus formation thus corroborating the hypothesis that iron accelerates thrombosis through a prooxidant mechanism.
Remarkably, prenatal TURP-induced increase in NAcc TH expression was also completely abrogated by maternal iron supplementation.
In the study performed by Ryndak et al., the amino terminus domain was shown to contain a FAD-binding domain and when mutated abrogated IrtAB function and iron utilization [ 107].
Iron chelation also abrogated binding of NCOA4 to exogenously expressed HERC2.
These data show that iron labeling does not abrogate phagocytosis.
Further supporting a role for HERC2 in regulating NCOA4 stability in the presence of high intracellular iron, overexpression of HERC2F3−6 abrogated NCOA4 loss following excess iron loading likely through interfering with the binding of NCOA4 to endogenous HERC2.
Likewise, NAC reduced acute generation of systemic oxidative stress but failed to abrogate proteinuria or enzymuria induced by 100 mg iron sucrose to CKD patients [ 11].
Replacing the iron coordinating Met with Leu did not abrogate high-affinity heme binding but did reduce the heme transfer rate constant by more than half.
