Sentence examples for abrogate her from inspiring English sources
This attitude forever alienated her from Hawaii's haole foreign businessmen who, after her accession, tried to abrogate her authority.
Monoclonal antibodies targeting the Her-2/ neu ectodomain, such as trastuzumab and its murine precursor 4D5, have been shown to abrogate the Her-2/ neu activation processes and to interfere with Her-2/ neu-dependent gene expression, to modulate cell cycle progression, induce cellular differentiation and to sensitise Her-2/ neu overexpressing cells to apoptotic stimuli.
Moreover, induction of the cdk4 inhibitor p15INK4B, a central mediator of TGF-β induced cell cycle arrest [ 58], was also abrogated by HER-2 overexpression in both MCF-7 and ZR-75-1 cells (Fig. 3b, asterisks).
On this score, Kadyrov hasn't done anything to abrogate his end of the bargain.
Few cases in this series expressed HER4 in isolation and it is increasingly apparent that co-expression of HER4 with other HER proteins may abrogate its protective effects [ 9].
In summary, these data indicate that HER-2 overexpression can abrogate TGF-β1 mediated gene induction without preventing ligand binding, Smad2 nuclear accumulation or Smad DNA binding.
We found that engineered HER-2 overexpression can abrogate TGF-β1 mediated gene responses in both MCF-7 and ZR-75-1 cells and can render the highly sensitive cell line (MCF-7) resistant to the growth inhibitory effects of TGF-β.
Since the weight of current evidence suggests that the predominant oncogenic function of HER3 is its ability to activate PI3K and Akt signalling, then it is a reasonable hypothesis that inhibitors of PI3K or Akt can also abrogate HER3 signalling and can potentially be used in combination with HER TKIs to develop much more effective therapies or to overcome HER TKI resistance.
Congressional proposals in 1879 to abrogate treaties reserving lands in Indian Territory to certain tribes aroused her to action.
The government cannot just abrogate contracts.
The Bush team will unilaterally abrogate it.
