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However, the above mentioned possibility of too small or too large SD, and correspondingly overestimated or underestimated SMD, should always be borne in mind in interpreting SMD.
To evaluate the above mentioned possibility, we applied our relative GC3 bias values to their results and found that ER-targeted enriched proteins had higher GC3 bias than those dis-enriched proteins (Mann-Whitney test, P < 1e−15; Fig. 1D).
Though the algorithm design of p-TAREF has capacity minimize the noise, especially those arising through mere complementarity, yet a couple of analyses were performed to verify the above mentioned possibility.
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In case it is not possible to use any of the above mentioned possibilities of solving mapping problems, it is necessary to cope with the fact that mapping will never be 100%.
We investigated the site of the [C]-Gal incorporation catalyzed by the recombinant proteins among the above mentioned possibilities by treating the [C]-Gal incorporated products made onto SP32-GFP and β-1,3-galactan with structure-specific hydrolases and subsequent size exclusion chromatography.
The above mentioned possibilities are further supported by the results of the present study.
The results were quite encouraging and suggestive of the possibility of using above mentioned approaches for immunocontraception.
However, one may not discard the possibility that alternative factors contribute to the above mentioned effect.
and the above mentioned traits.
Sesame lignans minimizes the above mentioned effects.
We are currently investigating the possibility to apply above mentioned strategy to all liganded GPCR clusters to define a global model for predicting ligands of new orphan GPCRs.
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