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STAT1 contributes necessary contacts with DNA which raises the affinity of ISGF3 for DNA above a minimal threshold provided by IRF9 alone.
The charismatic model predicts that schedules of exposure to cooperative agonists will favour a recurrence rate that is sufficient to maintain cooperative behaviours above a minimal threshold for each mission critical member of a cooperative group.
These data support the hypothesis that extra copies of SUL1, but not their absolute copy number above a minimal threshold nor the extent of flanking sequences, significantly affect the fitness of cells during growth under sulfate limitation.
To characterize and compare the roles of Arabidopsis PRMT5 and PRMT4 on pre-mRNA splicing, we evaluated their effects on annotated AS events from genes expressed above a minimal threshold level in all genotypes.
Likewise, the mild decreases in 12-pNCA activity were due to the fact that during neutral evolution the P450s were only required to maintain this activity above a minimal threshold (75% of the total 12-pNCA conversion of the parent protein when expressed in E. coli [ 16]).
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In a second set of experiments, we evaluated the effect of setting a minimal threshold on the external confidence.
Color-discrimination thresholds were determined in the positively stained areas with a minimal threshold of 500 pixels.
A minimal threshold was set and maintained for all images within each experiment.
We therefore intended to create a minimal threshold for participation and no interference with ongoing treatment.
The corresponding EST annotation was performed using a minimal threshold of e-6.
However, in vivo, protection was independent of immunoglobulin subclass, avidity, neutralization rate constant, and in vitro neutralizing activity; above a minimal avidity threshold, protection depended simply on a minimum serum concentration.
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