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The phrase "about the big difficulties" is correct and usable in written English.
It can be used when discussing significant challenges or obstacles in a particular context.
Example: "In our meeting, we need to talk about the big difficulties we faced during the project."
Alternatives: "regarding the major challenges" or "concerning the significant issues".
Exact(1)
But it actually says a lot about the big difficulties Tony Blair faces in getting the Scottish Labour party to modernise and adopt his New Labour agenda, an urgent task in the run-up to September's devolution referendum.Both Mr McMaster and Irene Adams, the MP for Paisley North, made enemies when they were picked to contest by-elections in 1990.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com