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To prevent abortive processing in vivo, the correct positioning of Drosha on the hairpin structure may be facilitated by additional co-factors.
These associated proteins may be required for the Drosha processing of specific miRNA sequences/structures or involved in the differential regulation of processing through 1) prevention of abortive processing, 2) alteration of the miRNA hairpin structure, 3) enhanced recruitment or positioning of Drosha on the hairpin, or 4) increased RNA cleavage activity.
Similar(58)
The changes in frq expression did not significantly alter the level of FRQ protein under identical conditions suggesting there may be an increase in abortive transcripts, a defect in processing mature frq mRNA, an increase in qrf, or a delay in translation.
So does processing.
Like, processing it mentally.
They're processing cocaine".
Feliciano nodded, processing it.
Insurers outsource claims processing.
"They are processing words".
One is processing power.
We're processing.
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