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Discover LudwigThe phrase "abolish function" is correct and usable in written English.
It can be used in contexts discussing the removal or elimination of a specific function or feature, often in technical or legislative discussions.
Example: "The committee decided to abolish function X due to its inefficiency in the current system."
Alternatives: "eliminate function" or "remove function".
Exact(4)
Changing a single favourable receptor-adaptor contact might result in a decrease in affinity of the complex but would not abolish function completely.
Although most of the mutations in StAR reduce or completely abolish function, the R181L mutant, which is predicted to affect lipid transfer but not binding [ 30], displayed wild-type levels of activity.
As with System I, the tyrosine might ligate the heme in CcmE*, but because heme ligation in CcmE is known to be dynamic and can accommodate alternative ligands, removal of the tyrosine (Y131A) does not abolish function.
Finally, C399A is part of a motif of four invariant cysteines in SpoIIE, and we observe synergistic effects of mutating multiple cysteines in tandem, suggesting that mutation of a single cysteine does not abolish function.
Similar(56)
P1-ovov454 confers orange/red periconfersth frequent corange/redectors attributed to alternative transpericarp events that abolish p1 function (Yu et al., 2011).
The G118A substitution abolished function as well.
Strikingly, this point mutant also largely abolishes function in ßcat destruction.
The effects of reduced or abolished function of the auxin transport regulator PID on lateral organ formation were enhanced in the rps10b-1 mutant background.
The molecular Cox15 sm/sm defect resembles that of the majority of mitochondrial disorders (i.e., partial rather than complete biochemical impairment) due to decreased but not abolished function of the mutant gene product.
While the W70A substitution completely abolished function, Q124A substitution attenuated stress fibre formation (seen in 35% of transfected cells compared with cells transfected with wild-type EspM2) while L118A and I127A reduced stress fibre formation by 56%and65%5% respectively (Fig. 4).
Mutations that disrupt Ca2+-binding to syt 7 abolish this function, suggesting that syt 7 functions as a Ca2+-sensor for replenishment.
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