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Most were unsure if an underlying physiological abnormality was responsible for symptoms or if muscle biopsy would demonstrate pathology, and many felt that underlying psychiatric illness contributed strongly to presentation.
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This abnormality is responsible for ineffective erythropoiesis in patients leading to severe anaemia with reticulocytopenia.
We speculated whether the generous inclusion criteria for liver function abnormality were responsible for the increased risk of neutropaenic fever.
Although outcomes following renal transplantation in patients with CFHR5 nephropathy have been generally good, the disease has been shown to recur following renal transplantation from an unrelated donor, proving that a circulating (as opposed to local) abnormality is responsible for pathology (Vernon et al., 2011).
It is thought that such abnormalities are responsible, at least in part, for the development and progression of neuroblastoma.
Therefore the structural sperm tail abnormalities are responsible for altered/absent sperm motility [ 37].
Chromosomal abnormalities are responsible for a substantial portion of reproductive problems.
These abnormalities are responsible for the presence of multilocular clinical and sub-clinical cancerous lesions that explains the increased risks of multiple cancers in this area.
The goal of this study was to examine whether metabolic abnormalities are responsible for the histological changes observed in Japanese patients with nonalcoholic fatty liver disease (NAFLD) who have undergone serial liver biopsies.
However, it remains unclear which metabolic abnormalities are responsible for the pathological progression of NAFLD, especially in Japanese patients, who generally are not severely obese compared with Western patients.
Because RPE is a main cell source producing PEDF in the eye, RPE abnormality could be responsible for decreased PEDF expression in the retinas of the DKO rd8 mouse.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com