Congenital and acquired anatomic abnormalities that interfere with the anatomy of the face can cause cognitive and psychological sequelae.
The infants will be enrolled if they are ≥ 38 weeks gestation, have a birth weight ≥ 2500 gm, and are without endocrine/chromosomal/genetic abnormality that could interfere with growth.
We excluded patients with any hypothalamic/pituitary disease, former cranial irradiation, prior significant head trauma, or any other medical condition or laboratory abnormality that may have interfered with the outcome of the study.
Gastrointestinal abnormalities that would interfere with intake or absorption of the study drug were also treated as criteria for patient exclusion.
Complicated UTIs are associated with conditions such as structural or functional abnormality of the genitourinary tract, or the presence of an underlying disease that interferes with host defence mechanisms, increasing the risks of acquiring infection or of failing therapy.
A total of 21 were excluded from participation (1) because they or their legal decision-maker declined to participate, (2) due to systemic or laboratory abnormalities that interfered with their participation or (3) because they were subsequently found to have missing data (VAS not recorded or incomplete vital signs on scheduled measurements).
According to the guidelines issued by the European Association of Urology (EAU), complicated UTIs (C-UTIs) are those associated with structural or functional abnormalities of the genitourinary tract, or with the presence of an underlying disease that interferes with host defence mechanisms, resulting in increased risk of acquiring infection or failing therapy.
Patients were excluded if they had a severe, acute, or chronic medical or psychiatric condition, or a laboratory abnormality that could increase the risk associated with study participation or study drug administration, or that could interfere with the interpretation of study results, or in the judgment of the investigator makes the patient inappropriate for entry.
Disk disease is a turtle — an abnormality that generally causes no harm.
It may even have inspired the defiant celebration of "abnormality" that marks Reed's greatest work.
