Sentence examples for abnormality plays an from inspiring English sources

The fact that p53 mutation abundance appears to increase during histological progression suggests that this abnormality plays an important driving role in carcinogenesis in Barrett's tissues.

These findings suggest that activation of β-catenin signaling, probably secondary to the gene abnormalities, plays an important role in the formation of the complex epithelial architecture in APAs, leading to inhibition of cell proliferation through overexpression of p21waf1.

43 Epigenetic abnormalities play an important role in carcinogenesis.

Lipoprotein abnormalities play an important role in the causation of diabetic atherosclerosis [ 39].

Cytogenetic abnormalities play an important role in diagnosing hematological malignant diseases and are important independent predictors of disease progression and survival.

As mitral valve leaflets and subvalvular apparatus abnormalities play an important role in the pathologies of obstructive HCM, surgical management of the mitral valve has been considered a vital part of myectomy [ 22].

Based on cytogenetic and clinical studies our patients were indicated for bone marrow transplantation at initial stages of MDS, where the cytogenetic abnormalities play an important role aiding to indicate and select these patients for this treatment, specially the pediatric patients.

We detected ~70 80% of the total apoptotic and necrotic fibers in aged rat quadriceps to be ETC abnormal further supporting the hypothesis that mtDNA deletions and the resultant mitochondrial enzymatic abnormalities play a causal role in the etiology of sarcopenia.

Endothelial abnormalities play a critical role in the enhanced activation of platelets and clotting factors that occur in diabetic patients.

Lipoprotein abnormalities play a key role in the pathogenesis of these diseases.

Pulmonary microcirculation abnormalities play a central role in pulmonary arterial hypertension (PAH) pathophysiology.