However, this abnormality may not result in abnormal brain 5-HT levels because 5-HT generally does not penetrate the blood brain barrier (BBB).
The presence or absence of any particular chromosomal abnormality may be of less clinical significance than the fact that abnormal lymphocytes populate the BM, and their presence correlates with reduced survival.
Conversely, in a number of menisci initially scored as degenerative, we no longer observed abnormal signal intensity on follow-up, suggesting that smaller areas of intrameniscal signal abnormality may be transient.
Children with the abnormality may experience developmental problems.
The abnormality may be a benign "normal variant" or may be something more serious.
Further characterization of the type of ANS abnormality may allow the development of novel pharmacologic therapies for these disorders.
Serum asymmetric dimethylarginine (ADMA) levels are increased in maintenance hemodialysis patients, and this abnormality may increase cardiovascular risk.
SAN deficits in schizophrenia have been linked to reality distortion, suggest that SAN abnormality may contribute to impaired salience that is associated with hallucinations and delusions in schizophrenia51.
This abnormality may be related to the mechanisms of action of mood stabilizers and the previous findings on the abnormal psychoimmunology of patients with bipolar disorder.
Yet had a doctor not done this simple test, the patient's abnormality may not have been picked up, and he would have been stuck taking medicine he didn't need and missing out on the sports he loved.
People with the abnormality may have no signs that anything is wrong, but brain scans show what looks like a change in neural connections.
