The phrase "abnormality known to" is correct and usable in written English.
It can be used when referring to a specific abnormality that is recognized or acknowledged by a particular group or individual.
Example: "The doctor discussed the abnormality known to affect the patient's respiratory system."
Alternatives: "anomaly recognized by" or "irregularity acknowledged by".
To date, there is no single genetic abnormality known to underlie HPS.
Interestingly, the increased expression of CX3CL1 directly correlates with the behavioral data that confirms thermal hypoalgesia (a sensory abnormality known to occur in NPP prior to hyperalgesia [ 36]).
None of the children had any other ophthalmological abnormality known to cause headache, including: convergence or accommodation insufficiency, heterophoria, heterotropia, or pseudotumor cerebri.
We first looked at groups of genes thought to be important for the beta-cell abnormalities known to occur in T2D.
Given the overlap in autism features with genetic abnormalities known to be associated with imprinting, one possible reason for lack of consistency would be the influence of parent-of-origin effects that may mask the ability to detect linkage and association.
b) Infants diagnosed with major congenital or chromosomal abnormalities known to affect gastrointestinal function c) Infants diagnosed with major congenital or chromosomal abnormalities known to affect head growth including definite parenchymal lesions on cranial ultrasound scan in first 48 hours.
Exclusion criteria: (i) infants with congenital abnormalities known to affect neurodevelopment and (ii) infants with non-English speaking parents.
Exclusion criteria: (i) infants with congenital abnormalities known to affect neurodevelopment (ii) infants requiring admission to neonatal intensive or special care nursery and (iii) infants with non-English speaking parents.
The hypoxia-specificity of HIF-1α target genes in vivo has been questioned due to the confounding influence of other microenvironmental abnormalities known to affect gene expression (e.g., low pH).
A heterogeneity of cellular deficits was also suggested by the Golgi apparatus abnormalities, occurring in a large proportion of motor neurons on many occasions in the absence of ATF3 or p53 expression, and being variable as compared to the relatively stereotyped Golgi abnormalities known to occur in other neurodegenerative conditions targeting motor neurons, such as ALS [ 24, 64].
Finally, Romidepsin was tested at the dose of 13 mg/m once a week in a cycle of 4 weeks in a clinical trial that divided patients with chromosomal abnormalities (known to aberrantly recruit HDAC-repressive complexes) and patients lacking in these abnormalities.
