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T2w-MRC diagnosed the abnormality in six (40%%) of these patients, whereas combined T2w-MRC and CE-MRC images detected the abnormality in 12 patients (80%%; P < 0.05; Fig. 3a, c).
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MR detected an abnormality in five patients (8%) in whom CT was negative.
Mammography failed to identify an abnormality in four patients (24%%), presumably due to overlapping dense breast parenchyma obscuring potential findings.
Ten patients (13%) had only one abnormality in their PCs, and for these, BM-lymphocytes had the same abnormality in three of them (30%).
The colposcopic evaluation of all five TCA cases excluded any cervical abnormality in three women with normal or borderline Pap smears.
Likewise, amplification of the 14q32 was detected in 23 (14%) patients with BM-lymphocytes bearing the same abnormality in two (9%) of them.
Moreover, in 46 subjects with IGT, an abnormality in four of five cardiovascular reflex tests, a greater heart rate variability, and increased heat detection thresholds have been shown recently (16).
Combined routine T2w-MRC and CE-MRC images achieved to demonstrate extravasation in 11 of these patients (84.6 %; P < 0.05), whereas T2w-MRC failed to identify the abnormality in seven patients (false-negative rate, 53.8 %; Fig. 1a-c).
Multivariate linear regression analysis was used to identify independent contributions of site ischaemia (diffusion and/or perfusion abnormality in seven Brodmann areas in language cortex), age, total volume of infarct (on diffusion-weighted imaging), and total volume of hypoperfusion (on perfusion-weighted imaging).
These architectural abnormalities included diffuse macular edema in 11 eyes (50 %), focal cystoid macular edema in 13 eyes (59%%), any intraretinal edema (diffuse or focal) in 17 of 22 eyes (77 %), both focal and diffuse macular edema in seven eyes (32%%), and retinal pigment epithelium abnormalities in six eyes (27%%).
Although CT revealed abnormalities in six patients, MD was suspected in only two.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com