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14 Unpublished data from the Newcastle group have demonstrated significantly lower anaerobic threshold (AT) values compared with patients with age-matched and sex-matched primary sclerosing cholangitis (PSC) and sedentary controls, again supporting a muscle bioenergetic abnormality contributing to the fatigue seen in PBC.
Recent longitudinal studies in children have shown that cardiovascular risk factors like blood pressure and triglycerides decreased with any degree of decrease in HOMA, independent of changes in weight status, supporting the hypothesis that insulin resistance is a key abnormality contributing to these cardiovascular risk factors [ 26].
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Functional and anatomical abnormality contribute to imbalance in IP [ 7].
Although other significant differences were detected, only gap between toes shows a consistent pattern as would be expected if a morphological abnormality contributed to the affected status.
Low HDLC levels are associated with an elevated blood viscosity, and this rheological abnormality contributes to cardiovascular risk (Thomas et al. 1999).
Early identification of patients at risk, both before admission and after discharge from ICU, may allow to prevent some of the physiologic abnormalities contributing to the APACHE II score.
Both circumstances generated placental abnormalities contributing to late-fetal and /or neonatal lethality phenotypes, respectively.
There appears to be a disturbance of trophic factors and glial cell function in addition to neurotransmitter abnormalities contributing to MDD.
(B) Patients with type 2 diabetes have an increased prevalence of lipid abnormalities, contributing to their high risk of CVD.
These findings suggest that there may be different vascular abnormalities contributing to brain dysfunction among diabetics compared with non-diabetics.
(E) Patients with type 2 diabetes have an increased prevalence of lipid abnormalities, contributing to their high risk of CVD.
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