The phrase "abnormality and at" is not correct and does not form a coherent expression in written English.
It appears to be an incomplete thought or phrase that lacks context, making it unusable as it stands.
Example: "The study focused on the abnormality and at the same time considered the environmental factors."
Alternatives: "irregularity and regarding" or "anomaly and concerning".
Chuxia Deng (NIDDK) described a tissue-specific mutation of BRCA1 in mammary epithelium [ 2], leading to chromosome abnormality and tumorigenesis at low frequency after a long period.
While such germ cells may be able to undergo normal fertilization, the effect of such disregulation, in combination with continuing abnormalities during cell division, would lead to developmental delay, embryo abnormalities, and death at early post-implantation stages as seen in our study.
Repeat MRI (at days 69 and 135 and month 11) showed marked resolution in signal abnormalities, and EEGs (at days 69 and 182) also showed considerable improvement.
Moreover, conditional deletion of both HDAC1 and HDAC2 in NSCs in mice results in severe brain abnormalities and lethality at postnatal day 7 [ 44].
Lack of Frabin/Fgd4 causes dysmyelination in mice in early peripheral nerve development, followed by profound myelin abnormalities and demyelination at later stages.
Unfortunately, there are few tests of renal function which are able to detect early functional abnormalities and which, at the same time, are suited for screening purposes by virtue of their simplicity, cost and safety.
Another disadvantage of this approach is that potential additional benefits conferred by current DSS would be lost, including early identification of other fetal abnormalities and pregnancies at risk of preeclampsia and intrauterine growth restriction (IUGR) [ 34].
"All one needed to do is design a drug directed at that abnormality and get a great response.
METHODS: Three hundred seventeen patients were tested for contrast sensitivity, Amsler grid abnormalities, and visual acuity at near and at distance.
In the acute toxicity study, all rats survived and did not manifest any sign of toxicity and abnormality at 1 and 2 g/kg dosage.
