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The most frequent causes, however, are chromosomal abnormalities that result in an inappropriately developing brain.
Breathing aside, most of these animals also have other genetic abnormalities that result in illness, from back problems to eye issues.
Down's syndrome, which is caused by an extra copy of chromosome 21, is one of many abnormalities that result from such a failure of homologous recombination in meiosis.
These results suggest that, with prolonged culture, these cells may spontaneously acquire further genetic abnormalities that result in uncontrolled proliferation.
Taken together, this evidence suggest that although there are many abnormalities caused by random components, cloned mice indeed exhibit common abnormalities that result from non-random components.
These findings support the notion that the progression of DCIS to invasive cancer may be due, in part, to MEC abnormalities that result in a loss of their normal tumor suppressor functions.
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Cytogenetical studies on primary duodenal AC revealed several abnormalities that resulted in partial or complete losses or gains chromosomally [ 67].
In addition to the ameliorating effects of Shb-deficiency on pathological angiogenesis, Shb knockout mice displayed vascular abnormalities that resulted in impaired recovery after ischemic injury [ 16].
This effect on blood oxygenation is seen not only in shunting but in any abnormality that results in a localized reduction in blood oxygen content.
Glaucoma is the name given to a group of diseases that cause a particular type of optic neuropathy (i.e., optic nerve disease or abnormality) that results in visual field loss.
Studies indicate that the effects of a vitamin D deficiency include an elevated risk of developing (and dying from) cancers of the colon, breast and prostate; high blood pressure and cardiovascular disease; osteoarthritis; and immune-system abnormalities that can result in infections and autoimmune disorders like multiple sclerosis, Type 1 diabetes and rheumatoid arthritis.
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