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In from 10percenttoto as many as 25percentt of women who develop cervical cancer, previous tests had missed cell abnormalities that required more frequent follow-up or treatment.
There were scads of false positives — abnormalities that required further CT scans and sometimes biopsies or surgery to rule out cancer.
Persons with abnormalities that required immediate investigation or treatment were referred to a local hospital.
No patient presented any symptoms in relation to these biliary abnormalities that required treatment to be stopped or a cholecystectomy.
An additional 14 patients had laboratory abnormalities that required further investigation, mainly hypercalciuria, uncontrolled treatment of thyroid disorders and low testosterone (in one man).
Unless there were abnormalities that required immediate attention (e.g. fractures or tumours), initial MRI findings were not reported to the general practitioner.
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But about a quarter of liver donors have anatomical abnormalities that require extra work.
Operations are of two general types: those that can be performed without a heart-lung machine, such as surgeries for patent ductus arteriosus and coarctation of the aorta, and those, such as intracardiac abnormalities, that require a heart-lung machine.
More than one-quarter of all arrests in children involve heart rhythm abnormalities that require use of a defibrillator to shock the heart into normal rhythm.
When imaging reveals abnormalities that require urgent action, or shows significant unexpected findings, the usual methods of communication may not be reliable enough to ensure that those responsible for clinical care of the patient act promptly.
Unique case reports and innocuous abnormalities that require no specific treatment were not included.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com