Sentence examples for abnormalities of systemic from inspiring English sources

Published data proved that aortic coarctation is not only a local anatomical pathology of the aortic isthmus but is associated with the persistent abnormalities of systemic precoarctational arterial function due to fibrosis and necrosis of the medial layer of arterial walls which leads to increased arterial stiffness and impaired reactivity [ 38– 40].

For example, compared with IL-21R-competent BXSB-Yaa mice for multiple parameters of SLE, the IL-21R-deficient Yaa mice showed none of the abnormalities characteristic of systemic lupus erythematosus (SLE) [ 3].

12 Treatment of UTI in patients with type 2 diabetes depends on several factors, including: presence of symptoms, if infection is localized in the bladder (lower UTI) or also involves the kidney (upper UTI), presence of urologic abnormalities, severity of systemic symptoms, accompanying metabolic alterations, and renal function.

Together, the association of these retinal microvascular abnormalities to systemic arteriosclerosis emphasizes that systemic arteriosclerosis can alter the microvascular environment of the optic nerve head.

Eligibility criteria included: gestation >37 weeks, vaginal delivery, birth-weight >2500 gm, APGAR at 5 min≥7 and absence of systemic abnormalities.

Laboratory abnormalities included the evidence of systemic inflammation with increased erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) and mild elevation of hepatic transaminase levels and hypochromic anemia in all patients.

This lack of translatability is at least in part due to lack of sufficient standardization in definitions and classification of cases of acute kidney injury (AKI), an incomplete understanding of the natural history of human AKI, and a limited understanding of how kidney injury interacts with other organ system failure in the context of systemic metabolic abnormalities.

As the most common cause of death in ALI/ARDS is multiple-organ-system failure, the systemic abnormalities of coagulation and fibrinolysis may be an important therapeutic target over the local pulmonary abnormalities.

Recent study showed that increased osteoclast formation and activity contributes to local and systemic abnormalities of bone remodeling, including bone erosion as well as focal and systemic osteoporosis [ 8].

Systemic abnormalities of haemostasis in cancer patients have increasingly been recognized, but whether this abnormal haemostasis bears any significance in the pathogenesis of the malignant process remains unclear.

Because of the complexity of the abnormalities of immune regulation in systemic autoimmunity, a few key B-cell abnormalities will be highlighted since they provide insight into the nature of perturbations of B-cell function that could contribute to autoimmunity, either in a causative manner or as a pathway that amplifies disease.