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Our previous work has shown that prenatal inhibition of the pathway produces abnormalities of brain development.
The notion that autism was caused by "refrigerator" mothers and absent fathers, promoted by psychoanalysts in the 1950's and 1960's, has yielded to the realization that the disorder is strongly rooted in genetics and abnormalities of brain development and function.
Recent recognition that altered perception of internal stimuli (interoception) plays a role in urgency urinary incontinence suggests that exploration of abnormalities of brain function in this disorder could lead to better understanding of urgency incontinence and its treatment.
"Here's a person who was looking for the physical underpinnings of abnormalities of brain function, and that is a difficult thing to do even today," said Dr. Jeff Lichtman, a developmental neurobiologist at Harvard who uses sophisticated computer imagery to map brain circuitry.
No abnormalities of brain parenchyma, parenchymal cerebellar or brainstem were found.
AMT-PET studies in patients with MDD suggested focal abnormalities of brain serotonin synthesis [23 26].
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Rather, it means that no abnormality of brain structure underlies them.
Therefore, MEG can be used to reveal the abnormality of brain activity in migraine with millisecond-level resolution.
Likely, Alzheimer's disease may also be related to abnormality of brain tissue stiffness [ 24].
MT ratio (MTR) is typically measured for the MT techniques and has been used for appraising abnormality of brain structures, especially those related to myelination.
The diversity of the pathological processes involved make it unlikely that there is a primary abnormality of brain iron metabolism common to these diseases, although this is the case with a group of rare genetic disorders characterized by neurodegeneration with brain iron accumulation (NBIA), [ 61].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com