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The bone abnormalities develop more slowly than kidney insufficiency; if the latter is severe, death may occur in childhood before the skeletal abnormalities become apparent.
As diabetes progresses, multiple metabolic abnormalities develop (hemostatic, inflammatory, neurologic, and oxidative), promoting CVD.
In addition, some authors hypothesized that the epididymis might be a site where sperm abnormalities develop [ 2, 3, 10, 11].
To examine how phenotypic abnormalities develop with aberrant karyotype, we profiled the transcriptomes of four human iPSC lines by RNA-seq technology on a next generation sequencing platform.
Global analysis of gene expression profiles and functional analysis of differentially expressed (DE) genes were implemented to examine how phenotypic abnormalities develop with aberrant karyotype.
We did expect this difference because this part of the skull base and skullcap is unequivocally affected in patients and abnormalities develop especially in the first decades.
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Most cardiac diseases in the newborn are caused by structural abnormalities developed in utero.
The time course with which the abnormalities developed and cleared, as well as the inverse relationship between the neuromuscular jitter and the firing rate in the abnormal muscles, indicated that the toxin caused the abnormalities in arm muscles.
NIH NINR R01NR013912; NSF 1320347; NHLBI-K08-HL122478 Figure 1 Random forest Area Under the Curve scores for accurate discrimination of real alerts vs. artifact in vital sign abnormalities developing in online continuous monitoring data.
Abnormalities developed in the remaining six patients by day 11 of illness.
In females, extreme floral abnormalities developed in which floral organs were transformed into bract or leaf-like organs bearing trichomes.
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