Sentence examples for abnormal subset from inspiring English sources

The competing hypothesis was that the CD8+ and DN cells expressing the HY transgenic TCR in male mice represent an abnormal subset of γδ lineage cells misguided by the premature expression of the transgenic TCRαβ that would mimic signals delivered normally by the TCRγδ.

Those cells are low-density PMNs and represent an abnormal subset of neutrophils present in peripheral blood mononuclear cell (PBMC) preparations from patients with lupus.

Our work on T cells in RA over several years has suggested that particular subsets are lost in RA notably recent thymic emigrants [ 9, 10] naïve and memory CD4+T cells, [ 9] regulatory T cells (Tregs) [ 11], and compensated by the presence of abnormal subsets (inflammation related cells, IRCs) [ 9].

In SLE, NETosis appears to be dysregulated due to an expansion of an abnormal neutrophil subset, the fact that type I interferons prime neutrophils for NETosis, and the presence of autoantibodies against LL37 and human neutrophil peptide that enhance NET formation and facilitate further plasmacytoid dendritic cells activation [ 65, 66].

We found highly unusual if not abnormal immune cell subsets in a number of ALS patients expressing CD16+ CD8+ and CD57+ or CD16+ cell CD57− cell surface clusters only in sporadic ALS with supranuclear palsy and in sporadic ALS with predominant involvement of the upper motor neuron.

Sections stained for CGRP, which in wild-type motor neurons is predominantly localized in the Golgi apparatus (Fig.  5a), revealed subcellular abnormalities suggestive of an abnormal Golgi apparatus in a subset of Ercc1 Δ/ − motor neurons (Fig.  5d).

Following MethyLight analyses, DNA remained from a subset of abnormal samples with greater sperm concentration.

Thus the uvh6-1 mutappearsears to exhibit abnormal regulation of a subset of genes rather than global defects in transcription (Hall et al. 2009).

(Recognition of famous faces was also tested and found to be abnormal for the UK subset of patients; refer to Supplementary Material).

Thus, the absence of Fbw7 appears to trigger abnormal differentiation of a subset of ductal cells, biasing them toward an endocrine fate.

This present study shows that even in a young cohort of patients with type 1 diabetes (average age 32.7 years at baseline) an abnormal VPT identifies a subset of patients with adverse cardiovascular risk parameters.