Exact(12)
Using MRI, her team detected a network of abnormal memory traces in the brains of people with this condition.
This finding may underlie the addicts' hypersensitivity on drug-related cues driven by abnormal memory processing [13], [31].
In contrast, detailed analysis of their memory deficits showed that the Syn2−/− mice had intact memory at 30-min, but abnormal memory at 2-hour, 1-day and 7-days (Figure 4c).
These criteria require (1) a memory complaint, (2) normal activities of daily living, (3) normal general cognitive function, (4) abnormal memory for age and (5) absence of dementia.
ADNI amnestic MCI subjects have MMSE scores in the 24 30 range, a memory complaint verified by an informant, abnormal memory function and a CDR score of 0.5 with preservation of general cognition and functional activities of daily living.
Low CD4+ lymphocytes and low TH2 type of cytokines i.e., IL-4, IL-10 which promote antibody function and functionally abnormal memory cells possibly accounted for low antibody titers in HIV infected patients.
Similar(47)
Another Fzd9−/− mouse showed abnormal spatial memory behaviours in the Morris water maze (Zhao et al, 2005).
A previous fMRI study in our cohort, however, reported a dose-dependent normalizing effect of VPA on abnormal working memory network activation with motor-cortex coactivation (Vollmar et al., 2011).
Our previous study demonstrated the irreversible effect of DEP on mouse heterochromatin configuration even after its removal as an abnormal epigenetic memory [ 12], and we examined whether chemical exposure has long-lasting effects after removal of the chemicals in human cell differentiation.
Indeed, over-expression of DYRK1A in some animal models is associated with a number of phenotypes, including heart defects and abnormal learning and memory (28, 33, 43– 43).
The main clinical features in this subgroup, such as low body weight, lactic acidosis, heart block, renal failure, deafness, male infertility, and abnormal long-term memory, has been reported previously (Inoue et al. 2000; Nakada et al. 2001, 2004, 2006; Ogasawara et al. 2010; Tanaka et al. 2008).
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