The phrase "abnormal lung development" is correct and usable in written English.
It can be used in medical or scientific contexts to describe atypical growth or formation of lung tissue.
Example: "The study focused on the effects of environmental factors on abnormal lung development in children."
Alternatives: "irregular lung growth" or "atypical lung formation."
Mice with targeted homozygous deletion of first Ig domain of Robo1/ died1 died at birth because of abnormal lung development, and few survivors eventually developed epithelial bronchial hyperplasia [ 6].
Kaartinen, V. et al. Abnormal lung development and cleft palate in mice lacking TGF-β3 indicates defects of epithelial-mesenchymal interaction.
Elevations in IGF-1 are associated with abnormal lung development in animal models of BPD (38) and human BPD lung samples (26, 39).
More research is warranted to improve our understanding of normal and abnormal lung development in relation to CDH.
"One of the most disturbing issues is that diesel particulate matter has been shown to cause abnormal lung development in kids," Dr. Frank James, a private practice physician in Bellingham, Wash., told The Huffington Post.
Additionally, defects in core fucosylation have been associated with abnormal lung development and an emphysema-like phenotype in Fut8 deficient mice [32], [33].
These findings suggest that sphingolipids play a role in abnormal lung vascular development through VEGF signaling in BPD.
Hypogenetic lung syndrome is primarily due to abnormal right lung development that has an anomalous pulmonary venous connection.
COPD subjects showed reduced SOX5 gene expression and abnormal embryonic lung development as well as decreased expression of the extracellular matrix molecule fibronectin were found in Sox5−/− mice.
Mouse knockout studies show that NFIA mutation results in hydrocephalus and abnormal brain development [8], NFIB mutation causes retarded lung development [9] and NFIC mutation causes abnormal tooth development [10], with very little overlap in phenotypes.
Bronchogenic cysts are thin-walled mucoid or serous cysts caused by anomalies in lung development due to abnormal budding of the ventral embryonic foregut.
