Sentence examples for abnormal lines from inspiring English sources

Rec8 is a meiosis-specific cohesin subunit, and in its absence only few abnormal LinEs are formed (Molnar et al. 1995, 2003; Lorenz et al. 2004).

Instead, derivation from a single blastomere may play a role, since Geens et al. [11], who succeeded in deriving hESC lines from embryos that were established for the study of early development, obtained a cytogenetically abnormal line.

Using two independent antibodies against Lamin A, we have observed that senescent fibroblast cells (GM9503 and IMR90) exhibit abnormal line-shaped Lamin A staining, similar to the Lamin A staining previously reported for senescent human mesenchymal stem cells [ 11, 44].

The following outcomes were measured: decreased level of consciousness measured as a GCS of < 15 and more severe central nervous system (CNS) depression as a GCS < 9; requirement for ICU admission; seizure activity; delirium, serotonin toxicity; an abnormal QT defined as the QT HR pair being above the abnormal line on the QT nomogram; and hospital LOS.

Overall, 37% (21/57) of cases had two or more abnormal cell lines (ranging from two to five abnormal cell lines).

Other common trisomies include trisomy 13 and 18. Mosaicism for a normal cell line and an abnormal cell line may occur in a single individual.

Different categories of abnormal cell lines were detected: (1) aneuploidy, including sex chromosome abnormalities and isochromosomes (22 cases), (2) ring or marker chromosomes (12 cases), (3) single deletion/duplication copy number variations (CNVs) (11 cases), (4) multiple deletion/duplication CNVs (5 cases), (5) exonic CNVs (4 cases), and (6) unbalanced translocations (3 cases).

The currently used control algorithms face difficulties in suppressing abnormal spectral lines caused by this inverse problem.

Up-regulation of VCP in at least two abnormal cell lines in MCF10AT model was confirmed by immunoblotting (Figure 3B).

However, FISH studies revealed two abnormal cell lines.

These cases typically involved multiple abnormal cell lines and presented the most challenge for interpretation by CMA alone.