Sentence examples for abnormal in structure from inspiring English sources

Blood vessels in tumors are abnormal in structure (dilated and torturous with abnormal basement membrane and inadequate pericyte coverage) and function (hyperpermeable; [11]. Tumor vessel leakiness correlates closely with histologic tumor grade [34].

We observed profound alterations in the pattern of intranuclear assembly of virions and viral protein inclusions in cells infected with fiber deletion mutants : a number of particles lacked their electron-dense core and the intranuclear crystalline inclusions of viral proteins visible in Ad5WT-infected cells were absent or abnormal in structure.

Vascular endothelial growth factor produced by tumour cells results in the formation of new vasculature that is abnormal in structure and more permeable than normal vasculature.

26 However, the transverse strains of the Achilles tendon were reduced in those with elevated BMI, suggesting that the collagenous matrix was not only larger, but abnormal in structure or composition.

Our detailed study is consistent with the correlation previously found between EGF receptor expression and stage and grade of bladder tumours, and suggests that at this level of analysis EGF receptors in bladder tumours are not abnormal in structure or size, autophosphorylation activity, or gene structure.

One possible reason is that the trachea used here was the cross section of main trachea tube originated from the spiracle, for the hardly observing any tracheole in the larvae using histological method, little knockdown of the SeCHSA transcript couldn't result in abnormal trachea in structure.

The new blood vessels produced within tumors by chronically activated angiogenesis ('angiogenic switch') are abnormal in their structure, distorted, enlarged, leaky and cause erratic blood flow and hemorrhagic lakes within the tumor [33].

It is well known that the IUGR placenta is often abnormal in both structure and function e.g. [ 22, 23].

Radiolabelling of tritiated mannose into tunicamycin-treated transformed patient fibroblast cells was performed to investigate whether GPI protein anchors in Family A were abnormal in their structure as well as their quantity, as occurs in peroxisomal disorders.

KLP10A has also been observed bound to cortical microtubules attached to the spindle pole bodies, implying a role in anchoring the spindle to the cortex – fly lines expressing a dominant-negative klp10A mutant showed oocyte spindles that were not only abnormal in overall structure, but were oriented more vertically to the cortex than wild type (Zou et al., 2008).

'Abnormalities in the spine: Anything abnormal in the structure of the lumbar spine will lead to sciatica.