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However, the most likely explanation for abnormal HR response involves abnormalities in autonomic nervous system modulation [ 17].
Moreover, we showed for the first time that C-SLE patients presented an abnormal HR response during and after the cardiorespiratory test (for example, low CR and delayed HR recovery), which are considered as important non-invasive markers of autonomic dysfunction [ 37- 39].
WRN deficient cells are also prone to abnormal HR at telomeric ends, and exhibit increased telomere loss, telomeric sister chromatid exchanges and spontaneous extra-chromosomal telomeric circles [26] [29].
This study indicates that patients with FM present abnormal HR response during and after exercise.
Patients with FM presented an abnormal HR response to exercise, suggesting cardiac autonomic impairment and higher risk of cardiac events and mortality.
However, the explanation for the association between abnormal HR recovery and an increased risk of death in various settings is not known.
Similar(53)
The presence of masked hypertension (normal clinic BP but abnormal 24-hr ABPM) [ 24] was also recorded.
Among 117 (53%) individuals with abnormal results (HR-HPV-positive and/or cytology was atypical squamous cells of undetermined significance or above), 67 underwent high resolution anoscopy.
These findings are partly in agreement with previous observations by Marrero et al. who showed enhanced sensitivity to esophageal acid perfusion in patients with symptoms of GERD, and abnormal 24-hr esophageal pH monitoring studies, but no histological evidence of esophageal inflammation (NERD+ group) as compared with healthy controls [ 37].
Adverse neurologic outcome in preterm infants could be associated with abnormal heart rate (HR) characteristics as well as with abnormal general movements (GMs) in the 1st month of life.
Because the patient was ill-appearing with significant tachycardia and an abnormal shock index (HR 150 beats per minute/BP 101 mm Hg = 1.5, abnormal >1) upon arrival to the ED, FocUS was performed in this patient who manifested a 'compensated shock state'.
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