Whether this abnormality reflects abnormal functional activity in the subcortical structures subserving tonic pain activation remains conjectural.
Also, to our knowledge, none have related abnormal functional organisation to brain structural abnormalities in SLI.
However, the present study establishes clear evidence for abnormal functional specialization within mrPFC in high-functioning participants with ASD, and the utility of multi-voxel pattern analysis techniques for investigating atypical populations.
It is possible that the widespread ICN abnormalities on electroencephalography in IGE derive from abnormal functional interactions between ICNs.
And the autonomic nervous system imbalance might be derived from the abnormal functional connections between the hypothalamus and other brain structures involved in autonomic function including the brain stem [16].
These findings suggest drug addicts' abnormal functional organization of the DMN, and are discussed as addiction-related abnormally increased memory processing but diminished cognitive control related to attention and self-monitoring, which may underlie the hypersensitivity toward drug related cues but weakened strength of cognitive control in the state of addiction.
Taking this explanation a step further because this area is a part of the language network [ 44] and ASD patients exhibit abnormal functional architecture of the superior temporal sulcus, these results may explain impaired language function and social interactions in ASD.
Abnormal functional connectivity was found in patients with writer's cramp as well as cervical dystonia.
This approach would help to understand abnormal functional behavior, complementing other studies of the consequences of structural damage, e.g. [78].
Schizophrenia is believed to result from abnormal functional integration of neural processes thought to arise from aberrant brain connectivity.
The multimodal MRI data provide specifically structural and functional evidences for the involvement of the thalamus in the abnormal functional connectivity between different brain networks between attacks.
