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In their study, any amount higher than 1% DHA resulted in a high percentage of abnormal fish, together with high mortality.
The study found a substantial proportion of abnormal fish.
Figure 2E and 2F show abnormal FISH from a representative field of view of the histologically benign section.
Our results may simply indicate there are favorable abnormal FISH changes that we have yet to discover.
In addition there was an intriguing association between advanced cardiac disease and abnormal FISH, especially monosomy 13/deletion 13/deletion
Figure 2B and 2C show abnormal FISH in a representative field of view of the tumour section.
Similar(39)
Median OS from diagnosis was 55 months (range: 0.1 119 months), with a significantly different survival between patients with abnormal cIg-FISH and no FISH abnormalities (43 months vs not reached P<0.0001).
No specific cIg-FISH abnormality was more prognostic than another; simply having any abnormal cIg-FISH finding resulted in a worse overall survival.
The findings demonstrated abnormal D-FISH results for 24 of 25 AFF19MLL, 19 of 20 MLLT4/MLL, all 20 MLLT3/MLL, all 18 MLL/ELL, and all 20 MLL/MLLT1 samples, confirming the efficacy of these D-FISH assays in detecting these common MLL/partner translocations.
Eighty-one percent of patients had an abnormal cIg-FISH.
On univariate analysis, having an abnormal cIg-FISH was associated with a worse survival (Table 3).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com