The phrase "abnormal expression of genes" is correct and usable in written English.
It can be used in scientific or medical contexts when discussing variations in gene activity that deviate from the norm.
Example: "The study revealed an abnormal expression of genes associated with the disease, indicating a potential area for further research."
Alternatives: "irregular gene expression" or "atypical gene activity."
In fact, one of our subjects exhibited a very abnormal expression of genes in a key metabolic pathway.
These new methods may provide a clearer picture of the difference between the structure of genes that are "on" and genes that are "off". As many cancers are driven by the abnormal expression of genes such as oncogenes and tumor suppressors, information about how DNA structure can turn genes on and off may aid in the development of cancer therapies.
The findings suggest that the molecular environment in which periosteal pain fibers exist contain abnormal expression of genes that promote inflammation; a condition that is likely to lower their activation threshold, when symptoms appear at the onset of an attack, or activate them chronically.
FTI treatment of cells from subjects with HGPS leads to a significant reversal of the abnormal expression of genes encoding proteins in the lamin A-Rb signaling network.
On the other hand, deletion or duplication on chromosome 1, 11 or 22, may lead to abnormal expression of genes which are all involved in cell lipid metabolism, including PLD5, LRP5L and AMBRA1.
We favor this interpretation, based on the reports of elevated anxiety observed in RTT patients and the abnormal expression of genes that are induced during the stress response by glucocorticoids [32], [33].
The changes of DNA methylation will result in abnormal expression of gene and produce various phenotypes such as pregnancy failure, congenital defects and acquired diseases.
This study sought to determine PC targeted genes and the expression of select PC targeted genes in OA menisci to test hypothesis that PC exerts its disease modifying activity in part by reversing abnormal expressions of genes involved in OA.
The hypothesis to be tested is that PC exerts its disease modifying activity, at least in part, by modulating the abnormal expressions of genes involved in the OA disease process.
This indicated that the abnormality of colon cell proliferation is because of the abnormal expression of related genes, but there were differentially expressed genes independent of experimental factors.
Although it is currently not clear how loss of DNA methylation at these sites affect gene expression, we propose that abnormal expression of these genes at specific cell types/developmental stages causes disturbances in downstream pathways such as degradation of target proteins.
