Sentence examples for abnormal expression of dna from inspiring English sources

For example, the abnormal expression of DNA methyltransferase led to spermatogenic defects, and JMJD3 (a histone H3K27 demethylase) regulated fragmentation of spermatogonial cysts.

Abnormal expression of these methylation-related enzymes may disturb DNA methylation in pediatric AML.

However, MYC activation by FBXW7 loss triggers activation of p53, which plays a key role in the regulation of cellular responses to DNA damage and abnormal expression of oncogenes.

The changes of DNA methylation will result in abnormal expression of gene and produce various phenotypes such as pregnancy failure, congenital defects and acquired diseases.

Amino acid deficiency, for example, causes a marked decrease in overall DNA methylation, along with abnormal expression of the normally silent, paternally imprinted and growth-related H19 allele in cultured mouse embryos (Doherty et al. 2000).

12 Typical epigenetic lesions in liver cancer include genome-scale changes in the DNA methylation landscape, loci-specific DNA hypermethylation, dysfunction of histone-modifying enzymes, and abnormal expression of ncRNAs.

These new methods may provide a clearer picture of the difference between the structure of genes that are "on" and genes that are "off". As many cancers are driven by the abnormal expression of genes such as oncogenes and tumor suppressors, information about how DNA structure can turn genes on and off may aid in the development of cancer therapies.

DNA aneuploidy is often observed in various tumors with abnormal expression of SAC factors 11.

DNA aneuploidy is observed in various human tumors and is associated with the abnormal expression of spindle assembly checkpoint (SAC) proteins.

Abnormal expression of RBFOX1/2 may play a role in neuroblastomas and glioblastomas12,13,14,15, epilepsy and mental retardation16.

How do you distinguish between a boy's normal fascination with violence and an abnormal expression of emotions?