The phrase "abnormal expansion" is correct and usable in written English.
It can be used in contexts discussing unusual growth or increase in various fields such as science, economics, or psychology.
Example: "The researchers observed an abnormal expansion of the tumor, indicating a more aggressive form of cancer."
Alternatives: "unusual growth" or "irregular increase".
Fragile X is a genetic form of mental retardation caused by an abnormal expansion of part of the X chromosome.
Bronchiectasis, an abnormal expansion of the bronchial tubes in the lungs as a result of infection or obstruction.
RNA toxicity was first described in myotonic dystrophy type 1, a multisystemic disorder caused by the abnormal expansion of a non-coding trinucleotide repeat sequence.
In addition, the altered function of APCs and a subset of monocytes which spontaneously secrete IL-1β and IL-6 in T1D determine the abnormal expansion of Th17 as well.
The huntingtin gene HTT, whose mutation is responsible for 90% of HD phenotypes contains a trinucleotide (CAG) repeat in its first exon; the mutation consists of an abnormal expansion of the repeat beyond a threshold of 35 units.
Huntington disease (HD) is a devastating neurologic disorder that is characterized by abnormal expansion of a CAG nt repeat in the first exon of the huntingtin (htt) gene, producing a mutant protein with an elongated polyglutamine stretch.
Here we show that abnormal expansions of TTTCA and TTTTA repeats in intron 4 of SAMD12 cause benign adult familial myoclonic epilepsy (BAFME).
Spinocerebellar ataxia type 6 (SCA6) is a neurodegenerative disorder caused by abnormal expansions of a trinucleotide CAG repeat in exon 47 of the CACNA1A gene, which encodes the α1A subunit of the P/Q-type voltage-gated calcium channel.
Thus, expression of both genes, FMR1 and DNMT1, is of interest in fresh and archival samples from individuals with diseases characterized by abnormal expansions within the CGG region.
Huntington's disease is a polyglutamine repeat disorder, dominantly inherited and caused by abnormal expansions of long glutamine sequences found in huntingtin (Venkatraman et al., 2004).
HD is an autosomal dominant condition caused by abnormal expansions in a CAG repeat tract in the huntingtin gene (HTT), resulting in an abnormally long poly-glutamine stretch in the protein which renders it aggregate-prone [8].
