Sentence examples for abnormal dat from inspiring English sources

The trend of increasing specificity with quantitative analysis is consistent with a study comparing initial DaT scan imaging diagnoses with 6-month clinical follow-up (Jennings et al., 2004), which reported an increase in specificity from 80%to100%0% when utilizing a cutoff of 30% decrease in age-corrected putamen uptake from normal controls to define abnormal DaT scans.

Whereas an abnormal DaT scan has been included as a suggestive diagnostic feature for DLB (McKeith et al., 2005), a normal DaT scan is consistent with Alzheimer's disease, ET, drug-induced parkinsonism, or in some cases vascular parkinsonism (Gerschlager et al., 2002; Sixel-Döring et al., 2011; Djang et al., 2012; Utiumi et al., 2012).

There was a significantly higher frequency of parkinsonism in the abnormal DAT SPECT group than the normal DAT SPECT group.

However, the incidence of these symptoms in patients with POLG mutations is higher than for other mitochondrial patients and abnormal DAT scans are often seen in these patients.

1 In total, 5 10% of patients with clinical dementia have intermediate (I FP-CIT SPECT scans, that I FP-CITrmal DAT binding, but not aSPECT ascansical of DLB.

The appearance of parkinsonism was significantly more frequent in patients from groups 1 and 2 that had abnormal DAT SPECT data, compared with patients from group 3 that had normal DAT SPECT data (group 1 vs group 3: p < 0.001; group 2 vs group 3: p < 0.001).

In the S+CF− group, putamen DAT binding was abnormal bilaterally in most cases (5/7).

We advocate that in adolescents or adults with a clinical picture of juvenile parkinsonism (onset <20 years) investigations for DTDS should be considered, including: (i) CSF neurotransmitter studies; (ii) DAT SPECT scan (abnormal in DTDS) (Kurian et al., 2011 a ); and (iii) SLC6A3 sequencing.

This reduction of DaT signal with age might affect diagnostic sensitivity of the technique if abnormal ioflupane [I] imaging was to show subtle or minimal change between normal and abnormal cases.

Taken together, if α-syn interferes with DA release [10], [12] and initial DA fibre loss results in above normal DAT levels (seen here), the net result could be less synaptic DA available for transmission and thereby abnormal motor behaviour.

"Spahk dat".