Sentence examples for abnormal channel from inspiring English sources

From a signal transmission perspective, signal loss due to dysfunctional signaling molecules can be understood by noticing C normal channel  = 1, whereas C abnormal channel  = 0.69 (see Methods).

Abnormal channel activity can contribute to the development and maintenance of painful neuropathies, which pose a large and persistent clinical problem [ 1].

In addition, the ΔF508-CFTR mutant is a dysfunctional channel that display abnormal channel gating characterized by a lower open probability than the wild type protein (Lukacs & Verkman, 2012).

Using the total probability theorem and by considering all the error events, we have calculated the transmission error probability for the pathological caspase3 channel, which is P e, abnormal channel  = 11/136 ≈ 0.08 (see Methods).

We have calculated the signaling capacity by applying the algorithm in Methods to the transition probability channel matrix, obtained from the channel transition probability diagram of the caspase3 abnormal channel.

A gain-of-function mutation (T635A) in the transient receptor potential (TRP) channel TRPC3 results in abnormal channel gating and causes cerebellar ataxia in the dominant Moonwalker (Mwk) mouse mutant.

"But obviously, it's going to be much easier to prevent the establishment of abnormal channels than to treat the ones already there".

Then all the HVGE features are evaluated with Kruskal-Wallis test to identify the abnormal channels.

The aetiology of lymphangioma is poorly understood but is believed to be a developmental abnormality characterised by failure of lymphatic tissue to establish normal communication with regional lymphatic vessels, resulting in dilatation of the abnormal channels [11].

However, other reports show increased intracellular calcium levels due to abnormal channelling activity (Deng et al., 2010; Landoure et al., 2010).

In patients carrying the CFTR G551D variant, which results in normal production of the CF transmembrane conductance regulator CFTR but abnormal chloride channel transport, ivacaftor specifically increases the channel gating activity of CFTR at the cell surface, thereby enhancing chloride transport and subsequently improving lung function in CF patients [ 21].