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Finally, this work may pave the way to the design of a new generation of devices which are able to trigger and tune specific biological outcomes.
Goal: The goal is to evaluate with regard to its correctness if stimuli generators automatically produced are able to trigger and feed a simulation until the end of its execution.
Ethylene is a gaseous hormone able to trigger and coordinate many physiological and response processes in higher plants, including ripening.
Despite the large body of data on the interactions between Src and HER2 in breast cancer [ 19- 21], it is still unclear how Src activation is able to trigger and sustain resistance to anti-HER2 antagonists.
Now, in eLife, Farrah Kheradmand, David Corry, James Tour and colleagues including Ran You as first author reveal important mechanisms by which these particles are able to trigger and sustain a permanent inflammatory process in the lungs (You et al., 2015).
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As Noggin and Sonic hedgehog (Shh) were recently shown to be required for early chick ventral skin formation, and able to trigger skin and feather formation from chick amnion, we associated cells engineered to produce those two factors with mouse amnion.
Indeed, the new dimeric SMAC-mimetics we present here are able to trigger rapid and complete degradation of cIAP1, and, consequently, to cause apoptosis in MDA-MB231 cells as single agents (data not shown).
They can also react autonomously to real-world events and influence it through processes that able to trigger actions and create services with or without direct human intervention.
For statistical analysis we selected two frequency bands of interests: theta and alpha in order to estimate whether presented stimuli were able to trigger attention and memory processes.
In mice, induced loss of imprinting and the subsequent overexpression of the imprinted Phlda2 gene were able to trigger placental and foetal growth retardation in the offspring whereas its deletion caused overgrowth [ 41 ].
These results suggest that the PLP-dependent enzyme AAT2 from B. subtilis is able to trigger hydrolysis and release of PLP from Pdx1, allowing transfer of this highly reactive co-factor to the PLP-dependent enzyme.
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