Aesthetic judgments are personal but not necessarily idiosyncratic, and we may well be able to sensitize others to what we find repellent or attractive.
Remarkably, all RCC cell lines analyzed were wild-type for p53, and a knockdown was likewise able to sensitize RCC cells to acute genotoxic stress.
Taken together, our findings suggest that TG is able to sensitize tumor cells of GCT to TRAIL-induced cell death, perhaps in part through up-regulating the death receptor DR5 and down-regulating the decoy receptor DcR1.
A novel polyamino polycarboxylic pyridine derivative ligand, N,N,N1,N1- 2,6-bis((3-(amiN,N,N1,N1- 2,6-bis1H-pyrazol-1-yl)methyl)pyridiN,N,N1,N1- 2,6-bisacid) (L), was designed and synthesized with the motive that it is able to sensitize the emission of lanthanides.
Therefore, BH3BAD and BH3NOXA although able to sensitize BH3BID, does not mimic this aBH3 [12], [12].
It is known that ethanol is also able to sensitize TRPV1 [65].
These data suggest that the functionally active PKCδ is able to sensitize NB cells to BSO and etoposide by inducing ROS overproduction and DNA damage.
Previously, we have reported that PL is able to sensitize cultured prostate cancer cells to apoptosis, in which caspases were activated [7].
Moreover, acyl-coenzyme A synthetase 5, which is solely expressed at the villus tip, is able to sensitize epithelial cells to apoptosis specifically triggered by the death ligand TRAIL [38].
Taken together, the data shown in Fig. 5 demonstrate that expression of NES-hTERT is able to sensitize SQ20B to γ-radiation and to oxidative stress caused by H2O2.
First, as XIAP-deficient myotubes are completely sensitive to cytosolic cytochrome c (Fig. 2b), a stimulus which is able to degrade or cleave XIAP and release cytochrome c would be able to sensitize myotubes to apoptosis.
