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Government departments will be able to pool data collected without having put in place robust privacy protections.
But only recently have enough good data been collected from enough places to carry out the sort of analysis Dr Hallal and his colleagues have engaged in.In all, they were able to pool data from 122 countries, covering 89% of the world's population.
Another strength of our study is that we were able to pool data at one point that was carefully selected based on descriptions in the protocols and representations of the figures.
To be able to pool data we required five or more studies for each threshold.
We were able to pool data for depression from all six studies.
A third potential limitation of this systematic review is the fact that we were not able to pool data for a quantitative analysis.
Where required and when the incidence of the outcome was rare, to be able to pool data, adjusted relative risks were calculated from adjusted odds ratios.
Third, because of important heterogeneity in the included studies, we were not able to pool data to perform a meta-analysis or to stratify data by clinically important subgroups (such as mild, moderate or severe PH).
When the DSR was established, it was decided to use the same patient-reported outcome as in the Swedish registry, mainly in order to be able to pool data and compare results.
This review suggests that while research may be able to pool data from past surveys, future surveys need to consider how their design can yield data comparable with previous surveys.
If we are able to pool data from more than 10 trials for the primary outcome, a funnel plot will be created and examined to explore possible small study biases.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com