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In our current study, however, we were not able to observed changes in bulk steady-state hMCPH1 levels in cultured human cells during the cell cycle.
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Using this information, the Grants have been able to observe changes in the beak shape and size of many finches and to understand how those changes have been shaped by natural selection.
"With something like the Antarctic ice sheet, some of these processes take centuries, and the amount of time we've been able to observe changes is at the maximum 20 years," Bingham said.
Furthermore, we were able to clearly track tumor growth and development longitudinally over several weeks and were able to observe changes in tumor size in response to chemotherapeutic treatment using this system.
It is important to point out that although the net exercise time was short; we still were able to observe changes in circulating levels of PGC1-α/irisin.
Although we were able to observe changes within each volunteer before, during and after HRV16 infection, we did not include a group of uninfected volunteers.
Being able to observe changes and potentially discover positive outcomes, can lead to new developments of products which can help those in need of an alternative to current practices.
Although we are able to observe changes in treatment with claims data, the reasons for adjusting or discontinuing treatment and thus their possible effects on patient outcomes are unknown.
The study has strengths and limitations: A strength is that we were able to observe changes for cost components in large patient samples gathered within the same study and in the same rheumatological units over 10 years.
Despite this it is noteworthy that we were able to observe changes in particular miR species in two separate cohorts of patients with metastatic prostate cancer compared with those with non-metastatic disease.
As long as the mutant follicle cells were still integrated in the epithelium, we were not able to observe changes in the distribution of DE-Cadherin or Crumbs (data not shown), indicating that sie is not essential for their normal distribution.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com