The phrase "able to modulate the expression of" is correct and usable in written English.
It can be used in scientific or technical contexts, particularly in discussions about genetics, biology, or any field where regulation of expression is relevant.
Example: "The researchers found that the new compound was able to modulate the expression of specific genes involved in cell growth."
Alternatives: "capable of regulating the expression of" or "able to adjust the expression of".
Using the hOE-MSCs model, we were also able to modulate the expression of IKBKAP WT and MU transcripts, by exposing the cells to different culture conditions to simulate variations in alternative splicing occurring during development and differentiation.
A quantitative real-time RT-PCR was performed to evaluate if resveratrol was able to modulate the expression of various genes known to be involved in NO signalling pathway.
In conclusion, our study shows that CHIK and DENV-2 are both able to modulate the expression of several mosquito's midgut proteins belonging to a variety of functional groups.
A number of pre-clinical studies have consistently demonstrated that DNA demethylating agents and HDAC inhibitors, either alone or in combination, are able to modulate the expression of a number of genes in ranges varying from 0.5 12% [55], [56], and that both classes of agents synergize not only the antitumor effects [4] [8], but also the extent of gene up-regulation [2], [3].
Moreover, saponins of P. notoginseng extract were able to modulate the expression of caspases and attenuate apoptosis in rats following focal cerebral ischaemia-reperfusion [ 4].
Also, it has been reported that the oxygenated derivative of DHA, Resolvin D1, is able to modulate the expression of specific miRNAs [ 119].
The key components in regulation of bacterial gene expression are DNA-binding transcription factors that are able to sense changing environmental conditions and to modulate the expression of relevant target genes.
More recently, p53 was demonstrated to modulate the expression of genes able to modify glucose as well as lipid metabolism, induction of autophagy, immune responses and cell motility [ 7- 11].
We demonstrated that, in our experimental conditions, TGF-β1 was able to induce the phosphorylation of Smad 3, known to modulate the expression of chondrocyte-specific genes, such as aggrecan [ 42].
Therefore, we investigated whether bufalin was able to modulate the protein expression of AKT and pAKT (Ser 473) in human hepatoma cells by western blot analysis.
It is still unclear which circulating mediators are able to modulate the TLR expression in NK cells.
