This test involves using short strands of RNA to block the expression of specific genes.
Doxorubicin-treated BMDM from Tnfr1−/− Il1r1−/− mice expressed lower amounts of IL-1β than WT BMDM (Fig. 2C), and anakinra was partially able to block the increase in gene expression following co-treatment with doxorubicin and vincristine (Fig. 3).
We should be able to block the deal by one of these ways".
Allopurinol was able to block the induction of MICA/B expression in the cells exposed to 5-FU, gemcitabine, or radiation.
Treatment with LLL12 was able to block the secretion of LIF and downregulate the expression of LIF, however the exact mechanism is unclear since LIF is not a target gene of STAT3 like IL-6.
Moreover, AQP3 mRNA silencing lasted for 96 hours since transfection, being able to block the up-regulation of AQP3 expression induced by 5′-DFUR treatment (data not shown).
Pretreatment with Y27632 was able to block the activation of ROCK induced by CA4P, as detected by p-ERM expression.
Norton was not able to block the installation of all the commercial keyloggers.
All of the envelopes tested elicited antibodies able to block the binding of rgp120 to CD4.
This was also able to block the increase of p-STAT3 (Fig. 6A).
Thus, IRF-7C is able to block the transactivation function of IRF-7.
