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Twelve patients (11.8%) did not meet at all, of whom 5 were not able due to work or private obligations, 4 gave no reasons, 2 on grounds of other diseases and 1 did not wish to participate.
We were not able, due to resource constraints, to have verification of grades by an independent assessor, and we felt it too invasive/burdensome to record skin sites photographically for remote checking.
We were not able to compare endostatin to known cardiovascular risk factors in our study and we were not able, due to missing data, to adjust for pro-brain natriuretic peptide serum levels, estimation of glomerular filtration rate levels or anti-RNA polymerase antibodies.
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We also understood that not everyone would want to or be able to move due to personal commitments.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com