Sentence examples for ability to replicate efficiently from inspiring English sources

It has been shown that laboratory adaptation of a duck H9N2 virus (A/Duck/Hong Kong/702/79) through serial lung passages in quail and chickens generated variant viruses that produced a large-plaque phenotype, showed rapid replication kinetics in tissue culture, and gained the ability to replicate efficiently in mice [47].

More importantly, the adapted virus gained the ability to replicate efficiently in mice when inoculated intranasally.

HSV-1 ICP0− mutant viruses are avirulent in immunocompetent mice, but acquire the ability to replicate efficiently and cause disease when host IFN signaling pathways are compromised [35], [37].

The high frequency of errors generated by HSV-2 6757 did not appear to preclude its ability to replicate efficiently in culture.

Mice that with components of the innate immune system knocked out, such as IFNAR-, PKR-, or STAT1-null animals, show lethality around 4 5 days after infection because of the virus's ability to replicate efficiently throughout the mouse [68]– [68].

Similarly, novel H1N1 is highly virulent in animal models, a property linked to its ability to replicate efficiently in the lungs [ 32], and likely attributable to lack of glycosylation.

The ability of SARS-CoV to replicate efficiently in kidney-derived cell lines is not surprising given that its functional receptor, the metalloprotease angiotensin-converting enzyme 2 (ACE-2), is highly expressed in kidney tissue (16 ).

In is possible that this observation could be attributable to differences in the ability of the bacterial species used to replicate efficiently between D. virilis and D. melanogaster, resulting in differences in the nature of the infection experienced by the two species of Drosophila.

The ability of these novel reassortant H5N8 viruses to replicate efficiently in the respiratory and intestinal tracts without killing the infected ducks enables them to circulate within the duck population and increases the possibility of transmission on poultry farms.

The attenuated poliovirus in the Sabin vaccine replicates very efficiently in the gut, the primary site of infection and replication, but is unable to replicate efficiently within nervous system tissue.

Conversely, highly pathogenic avian influenza (H5N1) and pandemic (H1N1) 2009 viruses have the ability to bind to avian-like influenza virus receptors on colonic epithelium and to replicate efficiently in intestinal cells and tissues (12 ).