Sentence examples for ability to model active from inspiring English sources

The ability to model active structures for agonist prediction would be particularly useful as active structures are difficult to crystallize.

The ability to homology model active GPCR structures would be a boon to the field, as agonists alone cannot fully stabilize the active conformation and are consequently harder to crystallize.

Although ultimately neither the homology model nor induced fit structures outperform the parent PI3K δ structure, 2WXL; this induced fit modeling approach is clearly useful for the development of homology models with good ability to discriminate active compounds from compounds in the decoy set.

Collectively, these results demonstrate the models' ability to discriminate between active and inactive compounds, suggesting that the models may be used to pre-screen compounds to facilitate compound optimization and to design novel inhibitors for drug development.

The formulate-ability of six model active pharmaceutical ingredients (API), with different physico-chemical profiles, in a nanoemulsion designed to be intraveinously administrable was explored.

The importance of the ability to discern between active and non-active states cannot be understated.

A PI3Kα homology model derived from a ligand-bound PI3Kδ crystal structure was developed that has a good ability to identify active compounds.

Descriptors were ranked by their ability to separate active from inactive molecules.

This financing may give BreezoMeter the ability to become active in serious health and medical markets.

All rats maintained their ability to distinguish active and inactive levers, under active-lever light illumination, as VRmax increased.

Most drugs have been developed based on their ability to bind active sites.