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The ability to make targeted gene modifications is the driving force behind reverse genetics.
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The ability demonstrated here to make targeted gene deletions is a powerful and direct tool for the investigation of in vivo gene function and the deletion of this endonuclease resulted in a strain that will provide the basis for further genetic manipulation.
This study demonstrates the ability to use sequence-specific nucleases in plants to make targeted chromosome rearrangements and create novel chimeric genes for reverse genetics and biotechnology.
Having demonstrated the ability to make synthetic repressors targeted to specific genes, we next sought to inhibit the transcription and replication of HIV-1.
However, designing tasks that target students' ability to make inferences can be challenging.
Without these types of studies, we lack the ability to make robust management recommendations for target levels of deer density to ensure the integrity of forest ecosystems in North America.
In science education, it is one of the most important goals for students to acquire the ability to make an appropriate model of the target system and its behavior for a given task.
The "skill" that we test is the ability to make straight reaching movements to different targets on a pen tablet.
Deafferented patients show a decreased ability to detect joint movement and an impaired ability to make accurate multi-joint movements to visual targets [4], and are unable to compensate for intersegmental interaction torques [5].
The main target was biology and its ability to make deadly micro-organisms.
The lower than targeted enrolment in the HIV-infected cohort limited our ability to make inferences on efficacy in that cohort.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com