The phrase "ability to activate the expression of" is correct and usable in written English.
It can be used in contexts related to biology, genetics, or any field discussing the regulation of gene expression or similar processes.
Example: "The research focused on the ability to activate the expression of specific genes in response to environmental changes."
Alternatives: "capacity to trigger the expression of" or "potential to induce the expression of".
By contrast, cells carrying rTFs with the DBD of 3F 3ZfFLO11/F1 (that was similar in DB affinity with 3ZfFLO11/F2, as determined by gel-shift assays) lacked any significant ability to activate the expression of FLO11.
In addition to their ability to activate the expression of genes linked to lipid metabolism, LXRs also have the ability to antagonize inflammatory gene expression triggered by Toll-like receptor (TLR) activation (Joseph et al., 2003, 2004; Castrillo et al., 2003a).
NF- κB is considered to have a critical role in the regulation of apoptosis due to its ability to activate the expression of many antiapoptotic genes, for example, TRAF and IAP proteins, c-FLIP, Bcl-XL and A1 (reviewed in Karin et al, 2002; Karin and Lin, 2002).
With respect to the ability of rTFs to activate the expression of FLO11, cells carrying rTFs with a DBD of 3F 3ZfFLO11/F2 (and an AD of either VP16 or VP64) appeared to be the most potent in activating expression of FLO11, resulting in a significantly altered phenotype.
In this work, we used the budding yeast Saccharomyces cerevisiae to study the ability of tailor-made zinc finger proteins to activate the expression of the FLO11 gene, with phenotypic consequences.
Specifically, alcohol induces oxidative stress in the lung at least in part by inducing the aberrant expression of TGF β1 expression which in turn suppresses Nrf2 expression and interferes with its ability to activate the ARE.
While co-expression of K13 strongly activated the CXCL10 promoters, vFLIP MC159 from the molluscum contagiosum virus, which resemble K13 in structure but lacks the ability to activate the NF-κB pathway [ 10, 25], failed to do so.
An engineered zinc finger protein (eZFP) was isolated from a library based on its ability to activate expression of the endogenous insulin gene in HEK-293 cells.
About 50% of all human cancers harbour mutations in the p53 gene, which affect its ability to activate expression of proapoptotic genes.
TNFα is a central mediator of the host inflammatory response by its ability to activate adhesion molecule expression, enhance leukocyte trafficking, and affect the expression of secondary cytokine cascades controlling leukocyte recruitment and activation [ 1, 2].
Another property of curcumin is the ability to activate NRF2 and induce the expression of antioxidant enzymes that are shown to protect normal tissue and organs during chemotherapy.
